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R&D Systems™ Recombinant Human B7-1/CD80 Fc Chimera Protein

Product Code. p-7180212
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Quantity:
1 mg
100 μg
Unit Size:
100µg
1mg
This item is not returnable. View return policy

Product Code. 18759896

Brand: R&D Systems™ 10133B1100

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This item is not returnable. View return policy

Description

Disulfide-linked homodimer

Measured by its ability to induce IL-2 secretion by Jurkat human acute T cell leukemia cells. Freeman, G.J. et al. (1993) Science 262:909. The ED50 for this effect is 0.025-0.15 μg/mL in the presence of PHA.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P33681
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Gene ID (Entrez) 941
Molecular Weight (g/mol) M.W. (Observed): 66-80 kDa, under reducing conditions; M.W. (theoretical): 50.5 kDa
Purification Method >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Quantity 100 μg
Source Chinese Hamster Ovary cell line, CHO-derived human B7-1/CD80 protein Human B7-1/CD80 (Val35-Asn242) (N-terminus) Accession # P33681 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
Endotoxin Concentration <0.10 EU / 1 μg of the protein by the LAL method.
Conjugate Unconjugated
Reconstitution Reconstitute at 500 μg/mL in PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose
Purity or Quality Grade >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Protein B7-1/CD80
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