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enQuireBio™ Recombinant Human Leptin tA Protein

A cDNA sequence encoding the Leptin tA was constructed and used to recombinantly synthesize the protein.

131.00 € - 203.00 €

Specifications

Name Leptin tA Protein
Regulatory Status Research Use Only
Endotoxin Concentration < 1.0 EU per ug protein as determined by the LAL method.
Biological Activity Capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Its in vitro activity is 6-8 fold lower than the non-pegylated antagonist but in vivo it has profound weight gain effect (as compared to the non-pegylated antagonist), resulting mainly from increased food intake. Its in vivo activity compared to that of PEG-MLA is 9-27 fold higher.
Product Type Recombinant Protein
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15985098
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enQuireBio™
QP10766-5UG
5 μg
131.00 €
5µg
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Estimated Shipment: 10-05-2024
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15975098
View Documents Promotion Details
enQuireBio™
QP10766-20UG
20 μg
203.00 €
20µg
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Estimated Shipment: 10-05-2024
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Description

Description

Specifications

Specifications

Leptin tA Protein
< 1.0 EU per ug protein as determined by the LAL method.
Recombinant Protein
E. coli
The protein was lyophilized from a concentrated (0.65 mg/ml) solution with 0.003mM NaHCO3.
Research Use Only
Capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Its in vitro activity is 6-8 fold lower than the non-pegylated antagonist but in vivo it has profound weight gain effect (as compared to the non-pegylated antagonist), resulting mainly from increased food intake. Its in vivo activity compared to that of PEG-MLA is 9-27 fold higher.
Human
Untagged
Greater than 98.0% as determined by: (a) Gel filtration analysis. (b) Analysis by SDS-PAGE.
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