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R&D Systems™ Recombinant Human Neuregulin-2/NRG2 Fc Chimera Protein

Product Code. 18785825
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100 μg
50 μg
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100µg
1mg
50µg
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18785825 100 μg 100µg
18766255 1 mg 1mg
18706005 50 μg 50µg
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Product Code. 18785825 Supplier R&D Systems™ Supplier No. 11354NR100

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Description

Carrier Free Recombinant Protein

Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48:4083. The ED50 for this effect is 10.0-100 ng/mL.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O14511.1
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Gene ID (Entrez) 9542
Molecular Weight (g/mol) MolecularWeight-observed: 67-76 kDa, under reducing conditions., MolecularWeight-theroretical: 59 kDa
Quantity 100 μg
Source Human embryonic kidney cell, HEK293-derived human Neuregulin-2/NRG2 protein Human NRG2 (Cys112-Lys404) (N-terminus) Accession # O14511.1 GGIEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
Endotoxin Concentration <0.10 EU / 1 μg of the protein by the LAL method.
Gene Alias divergent of neuregulin-1, Don-1, DON1, HRG2, neuregulin 2, Neuregulin2, NRG2, NTAK, NTAKneural- and thymus-derived activator for ErbB kinases, pro-neuregulin-2, membrane-bound isoform, Pro-NRG2
Conjugate Unconjugated
Reconstitution Reconstitute at 500 μg/mL in PBS.
Purity or Quality Grade >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Protein Neuregulin-2
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