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R&D Systems™ Recombinant Human Neuregulin-2/NRG2 Fc Chimera Protein
Description
Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48:4083. The ED50 for this effect is 10.0-100 ng/mL.
Specifications
Specifications
| Accession Number | O14511.1 |
| For Use With (Application) | Bioactivity |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Gene ID (Entrez) | 9542 |
| Molecular Weight (g/mol) | MolecularWeight-observed: 67-76 kDa, under reducing conditions., MolecularWeight-theroretical: 59 kDa |
| Quantity | 100 μg |
| Source | Human embryonic kidney cell, HEK293-derived human Neuregulin-2/NRG2 protein Human NRG2 (Cys112-Lys404) (N-terminus) Accession # O14511.1 GGIEGRMD Human IgG1 (Pro100-Lys330) (C-terminus) |
| Storage Requirements | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution. |
| Endotoxin Concentration | <0.10 EU / 1 μg of the protein by the LAL method. |
| Gene Alias | divergent of neuregulin-1, Don-1, DON1, HRG2, neuregulin 2, Neuregulin2, NRG2, NTAK, NTAKneural- and thymus-derived activator for ErbB kinases, pro-neuregulin-2, membrane-bound isoform, Pro-NRG2 |
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