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enQuireBio™ Recombinant Mouse Leptin tA Protein

Product Code. 15945098
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Quantity:
20 μg
5 μg
Unit Size:
20µg
5µg
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Product Code. 15945098

Brand: enQuireBio™ QP107645ug

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This item is not returnable. View return policy

Description

A cDNA sequence encoding the Leptin tA was constructed and used to recombinantly synthesize the protein.

Specifications

Name Leptin tA Protein
Quantity 5 μg
Regulatory Status Research Use Only
Endotoxin Concentration < 1.0 EU per ug protein as determined by the LAL method.
Biological Activity Leptin Antagonist Triple Mutant Mouse Recombinant half-life in circulation after SC injection was over 20 hours. Leptin Antagonist Triple Mutant Mouse Recombinant is capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Leptin Antagonist Triple Mutant Mouse Recombinant in vitro activity is 5-6 fold lower than the non-pegylated antagonist, though in vivo it has profound weight gain effect (as compared to the non-pegylated antagonist), resulting mainly from increased food intake.
Product Type Recombinant Protein
Cross Reactivity Mouse
Species E. coli
Protein Tag Untagged
Buffer The Mouse Leptin triple antagonist was lyophilized from a concentrated (0.65 mg/ml) solution with 0.003mM NaHCO3.
Purity or Quality Grade Greater than 99.0% as determined by:(a) Gel filtration analysis. (b) Analysis by SDS-PAGE.
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