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Tocris Bioscience™ Rotenone
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Product Code. 18792594
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50 mg
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Product Code. 18792594 Supplier Tocris Bioscience™ Supplier No. 3616/50
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Descripción

Inhibits complex I of the mitochondrial electron transport chain

Mitochondrial electron transport chain inhibitor (IC50 = 1.7 - 2.2 μM at complex I). Inhibits NADH oxidation by cardiac sarcoplasmic reticulum (IC50 = 3.4 nM). Commonly used pesticide and induces Parkinsonism in animal models. May also inhibit autophagy induction; blocks lysosomal degradation of autophagic vacuoles. Cell-permeable and brain penetrant.
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Especificaciones

CAS 83-79-4
Quantity 50 mg
Molecular Formula C23H22O6
Formula Weight 394.42
Purity >95%
Molecular Weight (g/mol) 394.423
Chemical Name or Material Rotenone
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