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Tocris Bioscience™ Rottlerin
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Product Code. 30001271
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Product Code. 30001271 Supplier Tocris Bioscience™ Supplier No. 1610/10

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Reported PKCδ inhibitor

Originally reported to inhibit PKC isoforms. Also reported to inhibit CAM kinase III. However, recently shown to inhibit a wide range of protein kinases, and most potently to inhibit PRAK and MAPKAP-K2 (IC50 values are 1.9 and 5 μM respectively). Also shown to act as a direct mitochondrial uncoupler. Thought to stimulate autophagy by targeting upstream mTORC1 control pathways.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 82-08-6
Molecular Formula C30H28O8

Specifications

Quantity 10 mg
Formula Weight 516.55
Purity >98%
Molecular Weight (g/mol) 516.546
Chemical Name or Material Rottlerin
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