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Invitrogen™ SARS-CoV-2 Spike Protein (RBD) (V367F) Fc Chimera Recombinant Protein

Product Code. 17986241
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity Unit Size
17986241 100 μg 100µg
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Product Code. 17986241 Supplier Invitrogen™ Supplier No. RP88398
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    487.72 € / 100µg
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Estimated Shipment: 15-12-2026
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Description

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (400 μL) be added to the vial to prepare a stock solution of 0.25 mg/mL. Concentration is measured by UV.

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. The CoV Spike (S) protein plays the most important roles in viral attachment, fusion and entry, and serves as a target for development of antibodies, entry inhibitors and vaccines. Of note is the Spike protein receptor-binding domain (RBD, S-RBD) in SARS-CoV-2 Spike protein which binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. SARS-CoV-2 RBD exhibits significantly higher binding affinity to ACE2 receptor than SARS-CoV RBD in comparison. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells.
TRUSTED_SUSTAINABILITY

Specifications

For Use With (Application) Binding Assay, Control, ELISA Standard
Format Lyophilized
Formulation PBS with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80 and no preservative; pH 7.4
Molecular Weight (g/mol) 51.54 kDa
Name SARS-CoV-2 Spike Protein (RBD) (V367F) Fc Chimera
pH Range 7.4
Purification Method Purified
Quantity 100 μg
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Endotoxin Concentration <1.0 EU/μg
Gene Alias Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
Common Name SARS-CoV-2 Spike Protein RBD
Biological Activity The SARS-CoV-2 (2019-nCoV) Spike RBD-mFc (V367F) Recombinant Protein can bind with Human ACE2 in functional ELISA assay.
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Protein Tag Fc-tag
Sequence SARS-CoV-2 spike RBD (Accession # YP_009724390.1), amino acids Arg319-Phe541 with a V367F substitution and a C-terminal mouse IgG1 Fc region
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Activity The SARS-CoV-2 (2019-nCoV) Spike RBD-mFc (V367F) Recombinant Protein can bind with Human ACE2 in functional ELISA assay.
Expression System HEK293 cells
Form Lyophilized
Purity or Quality Grade >90% as determined by SDS-PAGE.
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