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Thermo Scientific™ 2'-OMe-PAC-A Phosphoramidite, standard grade, serum vial bottle

Product Code. 17997102 Shop All Thermo Scientific Products
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Product Code. 17997102 Supplier Thermo Scientific™ Supplier No. 27182202

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2'-OMe-PAC-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-O-methyl protection, for use in oligonucleotide synthesis.

Ensure quality and reliability for RNA oligonucleotide synthesis with Thermo Scientific™ Standard RNA 2'-TBDMS, 2'-OMe and 2'-F Phosphoramidites.

2'-OMe-PAC-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 20-mL amber bottle with a serum vial neck style, which is compatible with most Applied Biosystems synthesizers and AKTA synthesizers.

Features:
Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl-2'-O-methyl-adenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Molecular formula: C49H56N7O9P
Base: A
Base Protection: PAC
Formula weight: 918.0 g/mol
CAS number: 128219-82-9
HPLC purity: ≥98.0%
31P NMR purity: ≥98.0%

TRUSTED_SUSTAINABILITY

Specifications

For Use With (Equipment) AKTA Synthesizers, Applied Biosystems Synthesizers
Product Type 2'-OMe-PAC-A CEP
Content And Storage Store in freezer (at or below -20°C).
Nucleoside Type Adenosine (A)
Reagent Features 2'-OMe modified, Fast deprotection
Shipping Condition Room Temperature
Purity 98%
Quantity 1 g
Reagent Type Phosphoramidite
Grade Standard
Nucleic Acid Type RNA
Form Powder
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For Research Use Only. Not for use in diagnostic procedures.

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