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Tacrolimus monohydrate, MedChemExpress

Product Code. 16491987
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Product Code. 16491987 Supplier Medchem Express Supplier No. HY13756A

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Description

MedChemExpress Tacrolimus monohydrate (FK506 monohydrate), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties.

Tacrolimus monohydrate (FK506 monohydrate), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties.

Specifications

Chemical Name or Material Tacrolimus monohydrate
CAS 109581-93-3
Color White
Purity Grade Notes Research
Molecular Formula C44H71NO13
Quantity 50 mg
Synonym FK506 monohydrateFujimycin monohydrateFR900506 monohydrate
Solubility Information DMSO : 100 mg/mL (121.65 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMILES O=C([C@@](CCCC1)([H])N1C(C([C@@]2(O)[C@H](C)C[C@H](OC)[C@@](O2)([H])[C@@H](OC)C[C@@H](C)C/C(C)=C/[C@H]3CC=C)=O)=O)O[C@H](/C(C)=C/[C@H]4C[C@@H](OC)[C@H](O)CC4)[C@H](C)[C@@H](O)CC3=O.O
Molecular Weight (g/mol) 822.03
Formula Weight 822.03
Percent Purity 98.0%
Grade Research
Physical Form Powder
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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