missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. STEMCELL Technologies Tamoxifen

STEMCELL Technologies Tamoxifen

Product Code. 17160102
Encompass_Preferred
Change view
Click to view available options
Quantity:
500 mg
5 g
10 g
Unit Size:
10g
500mg
5g
Product Code. Quantity unitSize
17160102 10 g 10g
17140102 500 mg 500mg
17150102 5 g 5g
3 options
This item is not returnable. View return policy

Product Code. 17160102

Brand: STEMCELL Technologies 72666

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Estrogen signaling pathway modulator; Modulates selective estrogen receptor and estrogen-related receptor

  • Tamoxifen is a selective estrogen receptor modulator (SERM), with tissue-specific antagonistic or agonistic effects
  • Receptor activation leads to the formation of homo- and hetero-dimers, which in turn interact with accessory proteins to regulate gene transcription
  • Tamoxifen is commonly used to activate Cre-ER in transgenic conditional models
  • Used in transgenic models to induce Cre-mediated recombination in conjunction with Cre-ER, a fusion protein consisting of Cre recombinase and a mutant form of the estrogen receptor hormone-binding domain that specifically binds tamoxifen but not estrogen (Feil et al.; Zhang et al.)
  • Inhibits growth in the human breast cancer cell line, MCF-7 (Katzenellenbogen et al.)
  • Antagonist of estrogen receptor action in breast tissue and breast cancer cells (Abe et al.; Horwitz et al.)

Specifications

CAS 10540-29-1
Synonym trans-Tamoxifen
Quantity 10 g
Molecular Formula C26H29NO
Purity ≥95%
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.