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Tocris Bioscience™ TC-S 7001
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Product Code. 18720779
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1 mg
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Product Code. 18720779 Supplier Tocris Bioscience™ Supplier No. 4961/1
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Estimated Shipment: 31-07-2026
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Description

Potent and highly selective ROCK inhibitor; orally active

TC-S 7001 (also known as BAY-549) is a potent and highly selective ROCK inhibitor (IC50 values are 0.6 and 1.1 nM for human ROCK1 and ROCK2, respectively), which exhibits >200-fold selectivity over TRK and FLT3 receptors, and >900-fold selectivity over a panel of other kinases and cardiovascular relevent enzymes and receptors. TC-S 7001 reduces blood pressure in normotensive and hypertensive rats, and is orally active.
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Specifications

Chemical Name or Material 6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine
CAS 867017-68-3
Synonym Azaindole-1
Quantity 1 mg
Target Rho-kinase Inhibitors
Molecular Formula C18H13ClF2N6O
Formula Weight 402.79
Purity >98%
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