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Temozolomide, MedChemExpress

Product Code. 16473317
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Product Code. 16473317

Brand: Medchem Express HY17364

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MedChemExpress Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects.

Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects.

Specifications

Chemical Name or Material Temozolomide
CAS 85622-93-1
Color Off-White
Purity Grade Notes Research
Molecular Formula C6H6N6O2
Quantity 50 mg
Synonym NSC 362856 CCRG 81045 TMZ
Solubility Information DMSO : 20.83 mg/mL (107.29 mM; Need ultrasonic) ∣H2O : 2.86 mg/mL (14.73 mM; Need ultrasonic)
SMILES O=C(C1=C(N2C=N1)N=NN(C)C2=O)N
Molecular Weight (g/mol) 194.15
Formula Weight 194.15
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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