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Tenidap, Tocris Bioscience™

Product Code. 30001379
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Product Code. 30001379 Supplier Tocris Bioscience Supplier No. 2580/10

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Description

NSAID, cyclooxygenase (COX-1) inhibitor. Also opener of KIR2.3

NSAID that preferentially inhibits COX-1 (IC50 values are < 0.03, 1.2 and > 30 μM for COX-1, COX-2 and 5-lipoxygenase respectively). Inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes. Opener of inward rectifying hKir2.3 channel (EC50 = 402 nM).
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 120210-48-2
Molecular Formula C14H9ClN2O3S
Molecular Weight (g/mol) 320.747
InChI Key LXIKEPCNDFVJKC-VAWYXSNFSA-N
Synonym tenidap sodium salt, dsstox_cid_26104, dsstox_rid_81342, dsstox_gsid_46104, e-5-chloro-3-hydroxy thiophen-2-yl methylene-2-oxoindoline-1-carboxamide, e-tenidap, 5-chloro-2-hydroxy-3-thiophene-2-carbonyl indole-1-carboxamide, 5-chloro-2-hydroxy-3-thiophen-2-ylcarbonyl-1h-indole-1-carboxamide, 5-chloro-2-hydroxy-3-thiophene-2-carbonyl-1h-indole-1-carboxamide, 5-chloro-2,3-dihydro-3-hydroxy 2-thienyl methylene-2-oxo-1h-indole-1-carboxamide
PubChem CID 54704052
IUPAC Name (3E)-5-chloro-3-[hydroxy(thiophen-2-yl)methylidene]-2-oxoindole-1-carboxamide
SMILES C1=CSC(=C1)C(=C2C3=C(C=CC(=C3)Cl)N(C2=O)C(=O)N)O

Specifications

Quantity 10 mg
Formula Weight 320.75
Percent Purity >99%
Chemical Name or Material Tenidap
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