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TG4-155, MedChemExpress

Product Code. 16457566
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Product Code. 16457566

Brand: Medchem Express HY18971

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Description

MedChemExpress TG4-155 is a potent, brain-permeant and selective EP2 receptor antagonist with a Ki of 9.9 nM. TG4-155 shows low nanomolar antagonist activity against only EP2 and DP1. TG4-155 has an EP2 Schild KB of 2.4 nM and displays 550-4750-fold selectivity for EP2 over EP1, EP3, EP4 and IP, but only 14-fold selectivity against the DP1 receptor.

TG4-155 is a potent, brain-permeant and selective EP2 receptor antagonist with a Ki of 9.9 nM. TG4-155 shows low nanomolar antagonist activity against only EP2 and DP1. TG4-155 has an EP2 Schild KB of 2.4 nM and displays 550-4750-fold selectivity for EP2 over EP1, EP3, EP4 and IP, but only 14-fold selectivity against the DP1 receptor.

Specifications

Chemical Name or Material TG4-155
CAS 1164462-05-8
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C23H26N2O4
Quantity 100 mg
Solubility Information DMSO : 125 mg/mL (316.89 mM; Need ultrasonic)
SMILES O=C(NCCN1C(C)=CC2=C1C=CC=C2)/C=C/C3=CC(OC)=C(OC)C(OC)=C3
Molecular Weight (g/mol) 394.46
Formula Weight 394.46
Percent Purity 99.69%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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