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Invitrogen™ Human TNK1, GST Tag Recombinant Protein

Product Code. 15930293
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Quantity:
1 mg
10 μg
100 μg
Unit Size:
100µg
10µg
1mg
This item is not returnable. View return policy

Product Code. 15930293

Brand: Invitrogen™ A30520

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Beschreibung

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This TNK1 recombinant human protein (1-510) was expressed in insect cells. TNK1 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. Validated for use with the Z'-LYTE™ assay Available in multiple pack sizes for convenient use Also available in our SelectScreen Kinase Profiling Service Protein Form: Recombinant, Active, Catalytic The gene accession number for TNK1 is NP_003976.2.

TNK1 tyrosine kinase, non-receptor 1 belongs to the tyrosine protein kinase family and as such is an important regulator of intracellular signal transduction pathways mediating cellular proliferation, survival, and development. TNK1 is highly expressed in fetal tissues and at lower levels in a few adult tissues. TNK1 may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. TNK1 plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene.
TRUSTED_SUSTAINABILITY

Spezifikation

Accession Number Q13470
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris HCl with 25% glycerol, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, 10mM glutathione, 150mM NaCl and no preservative; pH 7.5
Gene ID (Entrez) 8711
Molecular Weight (g/mol) 81.8 kDa
Name Human TNK1, GST Tag
pH Range 7.5
Purification Method Purified
Quantity 10 μg
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias CD38 negative kinase 1; Kinase of embryonic stem cells; Kos1; MGC46193; non-receptor tyrosine kinase; non-receptor tyrosine-protein kinase TNK1; TNK1; Tnk1a; Tnk1b; tyrosine kinase non receptor 1; tyrosine kinase, non-receptor 1; tyrosine kinase, non-receptor, 1
Common Name TNK1
Gene Symbol TNK1
KinaseFamily ACK Kinase Family
Protein Length 1-510
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence 1-510
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Assay Entry Biochemical phospho-specific activity (no antibody)
Shipping Condition Dry Ice
Target Entry TNK1
Expression System Insect cells
Protein Family Kinases & Inhibitors
Protein Form Recombinant, Active, Catalytic
Form Liquid
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