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Invitrogen™ Human TNK1, GST Tag Recombinant Protein
This TNK1 Recombinant Human Protein (1-510) was expressed in insect cells.
Brand: Invitrogen™ A30520
Additional Details : Weight : 0.01000kg
Description
- This TNK1 recombinant human protein (1–510) was expressed in insect cells
- TNK1 tyrosine kinase, non-receptor 1 belongs to the tyrosine protein kinase family
- It is an important regulator of intracellular signal transduction pathways mediating cellular proliferation, survival, and development
- TNK1 is highly expressed in fetal tissues and at lower levels in a few adult tissues
- TNK1 may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues
- TNK1 plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene
- TNK1 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
- Validated for use with the Z'-LYTE™ assay
- Available in multiple pack sizes for convenient use
Specifications
| NP_003976 | |
| 81.8 kDa | |
| ACK Kinase Family | |
| Human | |
| GST Tag | |
| Biochemical phospho-specific activity (no antibody) | |
| TNK1 | |
| Kinases & Inhibitors | |
| Liquid |
| Kinase Assay | |
| 10 μg | |
| aa 1 - 510 | |
| Recombinant | |
| Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. | |
| Dry Ice | |
| Baculovirus | |
| Recombinant, Active, Catalytic |