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VcMMAE, MedChemExpress

Product Code. 16486638
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Product Code. 16486638

Brand: Medchem Express HY15575

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Description

MedChemExpress VcMMAE (mc-vc-PAB-MMAE) is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).

VcMMAE (mc-vc-PAB-MMAE) is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).

Specifications

Chemical Name or Material VcMMAE
CAS 646502-53-6
Color Off-White
Purity Grade Notes Research
Molecular Formula C68H105N11O15
Quantity 10 mg
Synonym MC-Val-Cit-PAB-MMAE mc-vc-PAB-MMAE
Solubility Information DMSO : ≥ 54 mg/mL (41.01 mM)
SMILES CC(C)[C@@H](C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N2[C@@]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C3=CC=CC=C3)=O)([H])CCC2)=O)C)=O)=O)=O)C=C1)=O)=O)NC(CCCCCN4C(C=CC4=O)=O)=O
Molecular Weight (g/mol) 1316.63
Formula Weight 1316.63
Percent Purity 97.09%
Grade Research
Physical Form Solid
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Research purposes only

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