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WZ811, MedChemExpress

Product Code. 16496558
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Product Code. 16496558

Brand: Medchem Express HY15478

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Description

MedChemExpress WZ811 is an orally active, highly potent competitive antagonist of CXCR4. WZ811 efficiently inhibits CXCR4/SDF-1 (or CXCL12)-mediated modulation of cAMP levels (EC50=1.2 nM) and SDF-1 induced Matrigel invasion in cells (EC50=5.2 nM).

WZ811 is an orally active, highly potent competitive antagonist of CXCR4. WZ811 efficiently inhibits CXCR4/SDF-1 (or CXCL12)-mediated modulation of cAMP levels (EC50=1.2 nM) and SDF-1 induced Matrigel invasion in cells (EC50=5.2 nM).

Specifications

Chemical Name or Material WZ811
CAS 55778-02-4
Color White
Purity Grade Notes Research
Molecular Formula C18H18N4
Quantity 10 mg
Solubility Information DMSO : 10 mg/mL (34.44 mM; Need ultrasonic)
SMILES C1(CNC2=NC=CC=C2)=CC=C(CNC3=NC=CC=C3)C=C1
Molecular Weight (g/mol) 290.36
Formula Weight 290.36
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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