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HPLC Columns and Cartridges

Pre-packed columns, cartridges, and guard columns for separation of biomolecules and organic/inorganic analytes; includes normal/reversed phase HPLC, UHPLC, LC-MS, HILIC, mixed-mode, ion exchange, ligand exchange, and affinity column formats.
HPLC Columns (3,995)
HPLC Guard Columns and Cartridges (338)
HPLC Guard Column Accessories (43)

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1 – 15 of 1,026 results
1
Promotions Available

Thermo Scientific™ Hypersil™ BDS C18 Columns

Use as a robust, general-purpose column for a wide range of applications in QC/QA labs.

EDGE
Carbon Load 11%
Stationary Phase C18
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
Surface Area 170 m²/g
USP Type L1
2

Thermo Scientific™ Uniguard™ Direct-Connection Guard Cartridge Holders

Eliminate the requirement for extra fittings with Thermo Scientific™ Uniguard Direct-Connection Guard Cartridge Holders.

EDGE
Type Cartridge Holder
3
Promotions Available

Thermo Scientific™ Hypersil™ ODS C18 Columns

Use as a general purpose C18 phase for acidic and neutral analytes.

EDGE
Pore Size 120 Å
Carbon Load 10%
Stationary Phase C18
Temperature 60°C
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
pH 2 to 8
Surface Area 170 m²/g
USP Type L1
4
Promotions Available

Thermo Scientific™ Hypersil GOLD™ C18 Selectivity HPLC Columns
BIOPHARMA

Use these endcapped, ultrapure, silica-based columns to generate exceptional peak shape and resolution for HPLC and LC/MS analyses using generic gradients

EDGE
5
Promotions Available

Thermo Scientific™ Hypersil™ BDS C8 HPLC Columns

Use as a robust, general-purpose column for QC/QA applications. They are high-quality, base-deactivated, fully endcapped, have similar C18 selectivity but slightly less retentive.

EDGE
Pore Size 130 Å
Carbon Load 7%
Stationary Phase C8
Temperature 60°C
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
Surface Area 170 m²/g
USP Type L7
6
Promotions Available

Thermo Scientific™ Hypercarb™ Porous Graphitic Carbon HPLC Columns
BIOPHARMA

Use for enhanced retention of polar compounds and separation of structurally related analytes with stability at pH extremes and high temperature.

EDGE
7
Promotions Available

Thermo Scientific™ NativePac OBE-1 SEC Column for Online Sample Preparation

Perform Native-MS analysis of biomacromolecules with the NativePac OBE-1 SEC Column designed for rapid exchange of non-volatile buffer components with a volatile buffer.

EDGE
8

Thermo Scientific™ POROS™ CaptureSelect™ CH1-XL Affinity HPLC Columns

Thermo Scientific™ POROS™ CaptureSelect™ CH1-XL Affinity HPLC columns incorporate the advantages of high-speed POROS chromatography resins with the unique selectivity of CaptureSelect affinity ligands.

EDGE
Shipping Condition Wet Ice
Pore Size 2000 Å
Content And Storage Column includes EZ grip fittings and column test certificate.

Store at 2°C to 8°C. DO NOT FREEZE.
Stationary Phase IgG Fab affinity ligand, CH1 domain of human IgG antibodies
Temperature 2-40°C
Column Type Affinity
Quantity 1 Column
Material PEEK
Max. Pressure 2400 psi (170 bar)
Column Format Analytical Column, Biocompatible PEEK
Particle Size 20 μm
Packing Material Highly Crosslinked Styrene-Divinylbenzene polymer (ST-DVB)
Binding Capacity 26.2 mg/ml human IgG 8.8 mg/ml human Fab fragment
pH 1-10
Technique Bio-LC
Product Line POROS CaptureSelect
9
Promotions Available

Thermo Scientific™ Accucore™ C18 HPLC Columns
BIOPHARMA

Use this column, with its specially designed solid core, for a broad range of nonpolar analytes across multiple applications.

EDGE
Pore Size 80 Å
Particle Size 2.6 μm
Carbon Load 9%
Stationary Phase C18
Temperature 70°C
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
pH 1 to 11
Surface Area 130 m²/g
Particle Shape Spherical Solid Core
USP Type L1
10
Promotions Available

Thermo Scientific™ Single nanoViper™ and Double nanoViper™ PepMap™ Neo UHPLC Columns
BIOPHARMA

Separate challenging peptide mapping samples with Thermo Scientific™ Double nanoViper™ PepMap™ Neo UHPLC columns.

EDGE
Pore Size 100 Å
Particle Size 2 μm
Carbon Load 15%
Stationary Phase C18
Temperature 60°C
Endcapped Yes
Packing Material Spherical, Fully Porous, Ultrapure Silica
Column Type Reversed Phase
pH 2 to 8
For Use With (Application) Peptide Mapping, LC-MS
Max. Pressure 22,000 psi (1500 bar)
USP Type L1
11

Thermo Scientific™ POROS™ GoPure™ XS Pre-packed Column, 0.8 x 10 cm, 5 mL

Thermo Scientific™ POROS™ GoPure™ 0.8 cm pre-packed columns are intended for the screening of POROS affinity, ion exchange, and hydrophobic interaction chromatography (HIC) resins or for small scale purification.

EDGE
12

Thermo Scientific™ Accucore™ aQ C18 Polar Endcapped HPLC Columns

Use this column, with its specially designed solid core, for the separation of compounds in highly aqueous mobile phases.

EDGE
Pore Size 80 Å
Stationary Phase C18
Temperature 70°C
Phase Reversed Phase
Endcapped Polar
Column Type Reversed Phase
Surface Area 130 m²/g
Max. Pressure 14500 psi (1000 bar)
Particle Size 2.6 μm
Carbon Load 9%
Packing Material Spherical, Solid Core, Ultrapure Silica
pH 2 to 9
Particle Shape Spherical Solid Core
Product Line Accucore
USP Type L1
13

Thermo Scientific™ ProPac™ 3R SAX 3 μm HPLC Columns

Get the performance you need with ProPac™ 3R SAX HPLC columns. Suitable for charge variant separations and recommended for therapeutic proteins, mAbs, ADCs, and AAVs.

EDGE
Pore Size Nonporous
Particle Size 3 μm
Stationary Phase Proprietary
Temperature Ambient to 60°C
Phase Strong Anion Exchange
Packing Material Monodisperse Polymer Resin
Column Type Ion Exchange
pH 2 to 12
Technique Bio-LC
Max. Pressure 4500 psi (310 bar)
Product Line ProPac
Column Format Analytical Column
14
Promotions Available

Thermo Scientific™ µPAC™ Neo HPLC Columns

Learn more about your proteome samples with Thermo Scientific™ μPAC™ Neo Plus HPLC columns.

EDGE
Pore Size 100 to 300 Å
Stationary Phase C18
Endcapped Yes
Packing Material Silicon Chip
pH 1.5 to 7
Max. Pressure 6526 psi (450 bar)
15
Promotions Available

Thermo Scientific™ Acclaim™ Surfactant Plus HPLC Columns

Use for simultaneous separation of anionic, nonionic, cationic, and amphoteric surfactants with CAD and LC-MS detection.

EDGE
Pore Size 120 Å
Stationary Phase Proprietary
Temperature 50°C
Endcapped Yes
Packing Material Spherical, Fully Porous, Ultrapure Silica
Column Type Specialty/Application Specific
pH 2.5 to 7.5
Green Features Responsibly packaged
Surface Area 300 m²/g
Product Line Acclaim