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HPLC Columns and Cartridges

Pre-packed columns, cartridges, and guard columns for separation of biomolecules and organic/inorganic analytes; includes normal/reversed phase HPLC, UHPLC, LC-MS, HILIC, mixed-mode, ion exchange, ligand exchange, and affinity column formats.
HPLC Columns (3,996)
HPLC Guard Columns and Cartridges (341)
HPLC Guard Column Accessories (43)

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Keyword Search:
1 – 15 of 1,029 results
1
Promotions Available

Thermo Scientific™ Hypersil™ BDS C18 Columns

Use as a robust, general-purpose column for a wide range of applications in QC/QA labs.

EDGE
Carbon Load 11%
Stationary Phase C18
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
Surface Area 170 m²/g
USP Type L1
2
Promotions Available

Thermo Scientific™ Hypersil™ ODS C18 Columns

Use as a general purpose C18 phase for acidic and neutral analytes.

EDGE
Pore Size 120 Å
Carbon Load 10%
Stationary Phase C18
Temperature 60°C
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
pH 2 to 8
Surface Area 170 m²/g
USP Type L1
3
Promotions Available

Thermo Scientific™ EASY-Spray™ HPLC Columns
BIOPHARMA

Robust capillary flow HPLC columns for sensitive protein, peptide and mAbs separation using the stand alone or integrated easy to use design.

EDGE
Phase Reversed Phase
4
Promotions Available

Thermo Scientific™ Hypersil GOLD™ C18 Selectivity HPLC Columns
BIOPHARMA

Use these endcapped, ultrapure, silica-based columns to generate exceptional peak shape and resolution for HPLC and LC/MS analyses using generic gradients

EDGE
5
Promotions Available

Thermo Scientific™ Hypercarb™ Porous Graphitic Carbon HPLC Columns
BIOPHARMA

Use for enhanced retention of polar compounds and separation of structurally related analytes with stability at pH extremes and high temperature.

EDGE
6
Promotions Available

Thermo Scientific™ Acclaim™ PepMap™ 100 C18 HPLC Columns
BIOPHARMA

Use for high-resolution tryptic, natural, and synthetic peptide analyses. Its high loading capacity is exceptional for low abundant peptides in complex proteomic samples.

EDGE
Pore Size 100 Å
Stationary Phase C18
Phase Reversed Phase
USP Type L1
7

Thermo Scientific™ POROS™ G 20 μm Protein G Affinty HPLC Columns

Thermo Scientific™ POROS™ Protein G is based on an immobilized recombinant Protein G functional group designed for high throughput purification of antibodies.

EDGE
Particle Size 20 μm
Stationary Phase Recombinant Protein G
Binding Capacity 9 mg/mL
Column Type Affinity
Material PEEK
Product Line POROS
8

Thermo Scientific™ POROS™ CaptureSelect™ CH1-XL Affinity HPLC Columns

Thermo Scientific™ POROS™ CaptureSelect™ CH1-XL Affinity HPLC columns incorporate the advantages of high-speed POROS chromatography resins with the unique selectivity of CaptureSelect affinity ligands.

EDGE
Shipping Condition Wet Ice
Pore Size 2000 Å
Content And Storage Column includes EZ grip fittings and column test certificate.

Store at 2°C to 8°C. DO NOT FREEZE.
Stationary Phase IgG Fab affinity ligand, CH1 domain of human IgG antibodies
Temperature 2-40°C
Column Type Affinity
Quantity 1 Column
Material PEEK
Max. Pressure 2400 psi (170 bar)
Column Format Analytical Column, Biocompatible PEEK
Particle Size 20 μm
Packing Material Highly Crosslinked Styrene-Divinylbenzene polymer (ST-DVB)
Binding Capacity 26.2 mg/ml human IgG 8.8 mg/ml human Fab fragment
pH 1-10
Technique Bio-LC
Product Line POROS CaptureSelect
9
Promotions Available

Thermo Scientific™ Hypersil™ ODS-2 C18 Columns

Use as a general purpose C18 phase for acidic and neutral analytes separated under difficult operating conditions.

EDGE
Pore Size 80 Å
Carbon Load 11%
Stationary Phase C18
Temperature 60°C
Phase Reversed Phase
Endcapped Yes
Packing Material Spherical, Fully Porous Type A Silica
Column Type Reversed Phase
pH 2 to 8
Surface Area 220 m²/g
Max. Pressure 5800 psi (400 bar)
Product Line Hypersil Classical
USP Type L1
10
Promotions Available

Thermo Scientific™ Acclaim™ Trinity P2 HPLC Columns

Use these mixed-mode columns for separation of multivalent cations or anions and pharmaceuticals.

EDGE
Pore Size 300 Å
Solvents Compatible with most common HPLC organic solvents except for alcohols
Stationary Phase Spherical, Nanopolymer Hybrid Silica
Temperature 45°C
Phase HILIC and Ion Exchange
Endcapped Proprietary
Column Type Mixed Mode
Green Features FSC
Surface Area 100 m²/g
Max. Pressure 6000 psi (415 bar)
Particle Size 3 μm
Mobile Phase Compatibility 0 to 100% aqueous mobile phase
pH 2.5 to 7
Particle Shape Spherical silica
Product Line Acclaim
11
Promotions Available

Thermo Scientific™ Accucore™ Biphenyl Reversed Phase HPLC Columns
BIOPHARMA

Use this solid core column for fast and reliable separation of critical pairs and isomers.

EDGE
Pore Size 80 Å
Stationary Phase Biphenyl
Temperature 70°C
Phase Reversed Phase
For Use With HPLC/UHPLC Instrumentation
Endcapped Yes
Column Type Reversed Phase
Surface Area 130 m²/g
Max. Pressure 8700 psi (600 bar)
Particle Size 2.6 μm
Flow Rate 0.4 mL/min
Carbon Load 6%
Packing Material Spherical, Solid Core, Ultrapure Silica
Diameter (Metric) 2.1 mm
pH 2 to 8
Particle Shape Spherical Solid Core
Product Line Accucore
USP Type L11
12
Promotions Available

Thermo Scientific™ ProPac™ 3R SCX 3 μm HPLC Columns

Get the performance you need with ProPac™ 3R SCX HPLC columns. Suitable for charge variant separations and recommended for therapeutic proteins, mAbs, ADCs, and biosimilar proteins.

EDGE
Pore Size Nonporous
Particle Size 3 μm
Stationary Phase Proprietary
Temperature Ambient to 60°C
Phase Strong Cation Exchange
Packing Material Monodisperse Polymer Resin
Column Type Ion Exchange
Mobile Phase Compatibility Recommended for use with CX-1 pH buffers
pH 2 to 12
Technique Bio-LC
Max. Pressure 4500 psi (310 bar)
Product Line ProPac
Column Format Analytical Column
13
Promotions Available

Thermo Scientific™ Hypersil™ BDS C8 HPLC Columns

Use as a robust, general-purpose column for QC/QA applications. They are high-quality, base-deactivated, fully endcapped, have similar C18 selectivity but slightly less retentive.

EDGE
Pore Size 130 Å
Carbon Load 7%
Stationary Phase C8
Temperature 60°C
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
Surface Area 170 m²/g
USP Type L7
14

Thermo Scientific™ Uniguard™ Direct-Connection Guard Cartridge Holders

Eliminate the requirement for extra fittings with Thermo Scientific™ Uniguard Direct-Connection Guard Cartridge Holders.

EDGE
Type Cartridge Holder
15
Promotions Available

Thermo Scientific™ Accucore™ C18 HPLC Columns
BIOPHARMA

Use this column, with its specially designed solid core, for a broad range of nonpolar analytes across multiple applications.

EDGE
Pore Size 80 Å
Particle Size 2.6 μm
Carbon Load 9%
Stationary Phase C18
Temperature 70°C
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
pH 1 to 11
Surface Area 130 m²/g
Particle Shape Spherical Solid Core
USP Type L1