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CAS RN 48208-26-0

ONOHNOHO

CAS RN 48208-26-0

IUPAC Name: 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid
Synonyms: 2-(1,3-dioxoisoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid
Molecular Weight (g/mol): 334.33
Molecular Formula: C19H14N2O4
InChi Key: HPTXLHAHLXOAKV-UHFFFAOYNA-N
SMILES: OC(=O)C(CC1=CNC2=CC=CC=C12)N1C(=O)C2=CC=CC=C2C1=O

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2

Tocris Bioscience™ RG 108
GREENER_CHOICE

CAS: 48208-26-0 Molecular Formula: C19H14N2O4

CAS 48208-26-0
Molecular Formula C19H14N2O4
3

RG108, MedChemExpress

MedChemExpress RG108 (N-Phthalyl-L-tryptophan) is a non-nucleoside DNA methyltransferases (DNMTs) inhibitor (IC50=115 nM) that blocks the DNMTs active site. RG108 (N-Phthalyl-L-tryptophan) causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 334.33
Color Yellow
Physical Form Powder
Chemical Name or Material RG108
Grade Research
SMILES O=C(N1[C@H](C(O)=O)CC2=CNC3=C2C=CC=C3)C4=CC=CC=C4C1=O
For Use With (Application) Cancer-programmed cell death
Percent Purity 99.51%
CAS 48208-26-0
Solubility Information DMSO : 100 mg/mL (299.11 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
Synonym N-Phthalyl-L-tryptophan
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C19H14N2O4
Formula Weight 334.33
4

STEMCELL Technologies RG108

Epigenetic modifier; Inhibits DNA methyltransferase (DNMT)

ENCOMPASS_PREFERRED
CAS 48208-26-0
Purity ≥98%
Synonym N-Phthalyl-L-Tryptophan
Molecular Formula C19H14N2O4