CAS RN 854001-07-3

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Dasatinib hydrochloride, MedChemExpress

MedChemExpress Dasatinib (BMS-354825) hydrochloride is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib hydrochloride inhibits Bcr-Abl and Src with IC50s of apoptosis and autophagy.

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Specifications

Molecular Weight (g/mol)	524.47
Color	White
Physical Form	Solid
Chemical Name or Material	Dasatinib hydrochloride
Grade	Research
SMILES	O=C(C1=CN=C(S1)NC2=NC(C)=NC(N3CCN(CC3)CCO)=C2)NC4=C(C=CC=C4Cl)C.[H]Cl
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.01%
CAS	854001-07-3
Solubility Information	DMSO : 15 mg/mL (28.60 mM; Need ultrasonic and warming) ∣H2O : 10 mg/mL (19.07 mM; Need ultrasonic)
Synonym	BMS-354825 hydrochloride
Purity Grade Notes	Research
Recommended Storage	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Shelf Life	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molecular Formula	C₂₂H₂₇Cl₂N₇O₂S
Formula Weight	524.47

CAS RN 854001-07-3

CAS RN 854001-07-3

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