CAS RN 935888-69-0

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Oprozomib, TRC

CAS: 935888-69-0 Molecular Formula: C25 H32 N4 O7 S Molecular Weight (g/mol): 532.61 Synonym: ONX 0912,PR 047,O-Methyl-N-[(2-methyl-5-thiazolyl)carbonyl]-L-seryl-O-methyl-N-[(1S)-2-[(2R)-2-methyl-2-oxiranyl]-2-oxo-1-(phenylmethyl)ethyl]-L-serinamide IUPAC Name: N-[(2R)-3-methoxy-1-[[(2R)-3-methoxy-1-[[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide SMILES: COC[C@@H](NC(=O)[C@@H](COC)NC(=O)c1cnc(C)s1)C(=O)N[C@@H](Cc2ccccc2)C(=O)[C@@]3(C)CO3

Pricing and Availability
Specifications

CAS	935888-69-0
Molecular Weight (g/mol)	532.61
SMILES	COC[C@@H](NC(=O)[C@@H](COC)NC(=O)c1cnc(C)s1)C(=O)N[C@@H](Cc2ccccc2)C(=O)[C@@]3(C)CO3
Synonym	ONX 0912,PR 047,O-Methyl-N-[(2-methyl-5-thiazolyl)carbonyl]-L-seryl-O-methyl-N-[(1S)-2-[(2R)-2-methyl-2-oxiranyl]-2-oxo-1-(phenylmethyl)ethyl]-L-serinamide
IUPAC Name	N-[(2R)-3-methoxy-1-[[(2R)-3-methoxy-1-[[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
Molecular Formula	C25 H32 N4 O7 S

Oprozomib, MedChemExpress

MedChemExpress Oprozomib (PR-047) is an orally bioavailable and selective peptide epoxyketone proteasome inhibitor with IC50s of 36 and 82 nM for proteasome (β5) and immunoproteasome (LMP7), respectively. Oprozomib (ONX 0912) induces apoptosis in MM cells.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	532.61
Color	White
Physical Form	Solid
Chemical Name or Material	Oprozomib
Grade	Research
SMILES	C[C@]1(OC1)C([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H](NC(C3=CN=C(C)S3)=O)COC)=O)COC)=O)=O
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.5%
CAS	935888-69-0
Solubility Information	DMSO : ≥ 50 mg/mL (93.88 mM)
Synonym	ONX 0912 PR-047
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₅H₃₂N₄O₇S
Formula Weight	532.61

CAS RN 935888-69-0

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