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9-Fluorenylmethyl chloroformate, 98+%

Product Code. 11314629
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Product Code. 11314629

Brand: Thermo Scientific Alfa Aesar A11683.03

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Store cold | CAS: 28920-43-6 | C15H11ClO2 | 258.701 g/mol

Base sensitive amino protecting group for solid-phase peptide synthesis9-Fluorenylmethyl chloroformate is used in capillary electrophoresis. It acts as a reagent in the precolumn derivatization of amines for HPLC and fluorescent detection. Further, it is used for derivatizing amino acids for HPLC analysis. In addition to this, it is used to prepare N-Fmoc amino acids for solid-phase peptide synthesis and oligonucleotide synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Base sensitive amino protecting group for solid-phase peptide synthesis9-Fluorenylmethyl chloroformate is used in capillary electrophoresis. It acts as a reagent in the precolumn derivatization of amines for HPLC and fluorescent detection. Further, it is used for derivatizing amino acids for HPLC analysis. In addition to this, it is used to prepare N-Fmoc amino acids for solid-phase peptide synthesis and oligonucleotide synthesis.

Solubility
Soluble in dioxane.

Notes
Moisture sensitive. Store in a cool place. Incompatible with alcohols and amines.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 28920-43-6
Molecular Formula C15H11ClO2
Molecular Weight (g/mol) 258.701
MDL Number MFCD00001138
InChI Key IRXSLJNXXZKURP-UHFFFAOYSA-N
Synonym 9-fluorenylmethyl chloroformate, fmoc-cl, fmoc-chloride, fmoc chloride, 9h-fluoren-9-ylmethyl chloroformate, carbonochloridic acid, 9h-fluoren-9-ylmethyl ester, 9-fluorenylmethoxycarbonyl chloride, 9-fluorenylmethylchloroformate, 9h-fluoren-9-yl methyl carbonochloridate, 9h-fluoren-9-ylmethoxy carbonyl chloride
PubChem CID 34367
IUPAC Name 9H-fluoren-9-ylmethyl carbonochloridate
SMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)Cl

Specifications

Melting Point 60°C to 64°C
Assay Percent Range 98%
Quantity 1 g
UN Number UN2923
Beilstein 2279177
Sensitivity Moisture sensitive
Solubility Information Soluble in dioxane.
Formula Weight 258.7
Percent Purity 98%
Chemical Name or Material 9-Fluorenylmethyl chloroformate
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Signalwort
  • Danger
Gefahrenkategorie
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 1
  • Skin corrosion/irritation Category 1 B
Gefahrenhinweis
  • H302-Harmful if swallowed.
  • H312-Harmful in contact with skin.
  • H314-Causes severe skin burns and eye damage.
  • H318-Causes serious eye damage.
  • H332-Harmful if inhaled.
  • EUH029-Contact with water liberates toxic gas.
Sicherheitshinweis
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P302+P352-IF ON SKIN: Wash with plenty of water/.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.

RUO – Research Use Only

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