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Invitrogen™ A33 Recombinant Mouse Monoclonal Antibody (K92070_5D9)

Description
Immunogen sequence: LRASQGKSVT LPCTYHTSTS SREGLIQWDK LLLTHTERVV IWPFSNKNYI HGELYKNRVS ISNNAEQSDA SITIDQLTMA DNGTYECSVS LMSDLEGNTK SRVRLLVLVP PSKPECGIEG ETIIGNNIQL TCQSKEGSPT PQYSWKRYNI LNQEQPLAQP ASGQPVSLKN ISTDTSGYYI CTSSNEEGTQ Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 33%, Pig - 71%, Cynomolgus monkey - 90%.
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
Specifications
Specifications
| Antigen | A33 |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Recombinant Monoclonal |
| Clone | K92070_5D9 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.5% BSA, 50% glycerol and 0.09% sodium azide |
| Gene | Gpa33 |
| Gene Accession No. | Q99795 |
| Gene Alias | 2010310L10Rik; 2210401D16Rik; A33; A33 antigen; BB116197; cell surface A33 antigen; Glycoprotein A33; glycoprotein A33 (transmembrane); GPA33; mA33; MGC129986; MGC129987; transmembrane glycoprotein A33 |
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