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Invitrogen™ Acetyl-CoA Carboxylase Monoclonal Antibody (B.800.8)
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Product Code. 11564991
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
11564991 100 μL 100µL
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Product Code. 11564991 Supplier Invitrogen™ Supplier No. MA515025

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Description

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody.

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Acetyl-CoA Carboxylase
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone B.800.8
Concentration 210 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 0.15M NaCl, 50% glycerol, 100 μg/mL BSA and <0.02% sodium azide; pH 7.5
Gene Acaca
Gene Accession No. P11497, Q13085, Q5SWU9
Gene Alias A1Z784_DROME; A530025K05Rik; Acac; Acaca; ACACAD; Acc; ACC1; ACCA; ACC-alpha; ACC-PA; ACC-PB; ACC-PC; ACC-PE; ACC-PF; ACC-PG; aceto-acetyl-CoA-thiolase; acetyl CoA carboxylase; acetyl coenzyme A carboxylase; Acetyl-CoA carboxylase; Acetyl-CoA carboxylase 1; acetyl-CoA carboxylase 265; acetyl-CoA carboxylase alpha; acetyl-CoA-carboxylase; acetyl-coenzyme A carboxylase; acetyl-coenzyme A carboxylase alpha; ACoT; Biotin carboxylase; CG11198; CG11198-PA; CG11198-PB; CG11198-PC; CG11198-PE; CG11198-PF; CG11198-PG; CG8723; dACC; DmACC; Dmel\CG11198; Dmel_CG11198; EC 6.3.4.14; EC 6.4.1.2; FBgn0043811; GH12002p; Gm738; I79_006999; unnamed protein product
Gene Symbols Acaca, ACC
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues surrounding Ser523 of human acetyl-CoA carboxylase a1.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100762904, 104371, 107476, 31, 60581
Target Species Human, Mouse, Rat, Hamster
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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