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Invitrogen™ ALAS2 Recombinant Rabbit Monoclonal Antibody (K01_1M51)
Description
Immunogen sequence: SEWERSYFGN MGP.
ALAS2 specifies an erythroid-specific mitochondrially located enzyme. It catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
Specifications
Specifications
| Antigen | ALAS2 |
| Applications | Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | K01_1M51 |
| Concentration | 0.60 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 50mM tris glycine with 40% glycerol, 0.05% BSA, 150mM NaCl and 0.01% sodium azide; pH 7.4 |
| Gene | ALAS2 |
| Gene Accession No. | P08680, P22557, Q63147 |
| Gene Alias | 5'-aminolevulinate synthase 2; 5-aminolevulinate synthase 2; 5-aminolevulinate synthase, erythroid-specific, mitochondrial; 5-aminolevulinic acid synthase 2; ALAS; Alas2; Alas-2; alas2 protein; Alase; ALAS-E; Aminolevulinate synthase 2, delta; aminolevulinate synthase erythroid specific isoform; aminolevulinate, delta-, synthase 2; aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia); aminolevulinate, delta-, synthetase 2; aminolevulinic acid synthase 2, erythroid; ANH1; ASB; cb1063; Delta-ALA synthase 2; delta-ALA synthetase; delta-ALA synthetase 2; delta-aminolevulinate synthase 2; erythroid aminolevulinate synthase; erythroid-specific ALAS; erythroid-specific delta-aminolevulinate synthase ALAS-E; heme biosynthetic enzyme; PRO2399; RP5-884M20.1; sau; sauternes; si:dkey-24f17.4; SIDBA1; XLDPP; XLEPP; XLSA |
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