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Invitrogen™ Alpha Sarcoglycan Recombinant Rabbit Monoclonal Antibody (K01_1M66)

Product Code. 30830430
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30830430 50 μL
30828471 100 μL
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Product Code. 30830430 Supplier Invitrogen™ Supplier No. MA564590

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Rabbit Recombinant Monoclonal Antibody

Alpha Sarcoglycan Recombinant Monoclonal Antibody for Western Blot

The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac, and smooth muscle fibers. Four sarcoglycan subunit proteins, designated alpha-, beta-, gamma- and delta-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, beta- and delta-sarcoglycans are associated with epsilon-sarcoglycan, a glycoprotein homologous to alpha-sarcoglycan. Additionally, a complete deficiency in delta-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Alpha Sarcoglycan
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_1M66
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 150mM NaCl, 0.05% BSA, 40% glycerol and 0.01% sodium azide; pH 7.4
Gene SGCA
Gene Accession No. P82350, Q16586
Gene Alias 50 kDa dystrophin-associated glycoprotein; 50DAG; 50kD DAG; adhalin; ADL; Alpha-sarcoglycan; alpha-SG; Asg; DAG2; DMDA2; Dystroglycan 2; Dystroglycan2; dystroglycan-2; LGMD2D; limb girdle muscular dystrophy 2D; sarcoglycan alpha; sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein); sarcoglycan, alpha (dystrophin-associated glycoprotein); SCARMD1; SG alpha; SG-alpha; Sgca
Gene Symbols SGCA
Host Species Rabbit
Immunogen A synthetic peptide of human alpha Sarcoglycan.
Purification Method Protein A/G
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20391, 303468, 6442
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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