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  6. Thermo Scientific Chemicals Amphotericin B, 85%

Thermo Scientific Chemicals Amphotericin B, 85%

Product Code. 15535156 Shop All Thermo Scientific Chemicals Products
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Code produit 15535156 Fournisseur Thermo Scientific Chemicals Code fournisseur 455490010
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Description

Amphotericin B, CAS # 1397-89-3, is an antifungal that has been used against fungus caused by protozoan parasites of Leishmania genus. | CAS: 1397-89-3 | C47H73NO17 | 924.09 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Amphotericin B is an antibiotic that has antifungal activity and is produced mainly by Streptomyces nodosus

Applications

• It has antifungal activity against fungus caused by protozoan parasites of Leishmania genus by binding to an essential component of the fungal cell membrane and altering cell membrane permeability

• It can suppress bone marrow progenitor cells and induce Actinomycin D(CR001) sensitivity in drug resistant HELA cells in vitro

TRUSTED_SUSTAINABILITY

Identifiants chimiques

CAS 1397-89-3
Molecular Formula C47H73NO17
Molecular Weight (g/mol) 924.09
MDL Number MFCD00877763
InChI Key APKFDSVGJQXUKY-ZNVUZQDLSA-N
PubChem CID 134129663
SMILES C[C@H]1O[C@@H](O[C@@H]2C[C@@H]3O[C@@](O)(C[C@H](O)[C@H]3C(O)=O)C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)\C=C/C=C\C=C/C=C\C=C/C=C\C=C/2)[C@@H](O)[C@@H](N)[C@@H]1O

Spécification

Type Amphotericin B
Melting Point >170.0°C
Water 10% max.
Quantity 1 g
Solubility Information Solubility in water: insoluble.
IUPAC Name (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19Z,21Z,23Z,25Z,27Z,29Z,31Z,33R,35S,36R,37S)-33-{[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
Formula Weight 924.09
Percent Purity 85%
Chemical Name or Material Amphotericin B

Sécurité et traitement

compliance-icons
Identifiant produit
  • Amphotericin B
 Mention d'avertissement
  • Warning
 Catégorie de danger
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Mention de danger
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
  • H315-Causes skin irritation.
 Conseils de prudence
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
FDS

RUO – Research Use Only

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