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  6. Invitrogen™ ANKRD26P1 Recombinant Mouse Monoclonal Antibody (K40073_16B3)

Invitrogen™ ANKRD26P1 Recombinant Mouse Monoclonal Antibody (K40073_16B3)
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Product Code. 30827092
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30830397 50 μL
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Product Code. 30827092 Supplier Invitrogen™ Supplier No. MA564426

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Description

Mouse Recombinant Monoclonal Antibody

Immunogen sequence: HHANIESANK DELTPFLLAV HEQKQQMEDF LRKQKENLTA VKLESIHQVM SEYKENETPR NPQNSNPEGT SNKMACLGEG AAGAKVDEIP GNPVKRLFNK PSIDDSRPMS ANEDFDFDTE EKATEPANGK Highest antigen sequence identity to the following orthologs: Mouse - 39%, Pig - 46%, Cynomolgus monkey - 95%.

ANKRD26P1 is a pseudogene closely related to the ANKRD26 gene, which is located on chromosome 10 and is characterized by having ankyrin repeat domains. The ANKRD26 gene plays a vital role in signal transduction and is implicated in hematological disorders, including inherited thrombocytopenia. This gene is involved in the regulation of type I cytokine receptor signaling, contributing to the maintenance of blood platelet levels and the immune response. Its mutations are associated with thrombocytopenia 2 (THC2), a condition marked by low platelet counts and an increased risk of developing hematologic malignancies. While ANKRD26 is actively transcribed and translated into a functional protein, ANKRD26P1, being a pseudogene, does not produce a protein product. Pseudogenes like ANKRD26P1 are sequences in the genome that resemble known genes but are typically non-functional due to mutations or lack of regulatory features necessary for expression. The presence of pseudogenes can still be biologically relevant, as they may play roles in gene regulation and evolution despite not encoding proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ANKRD26P1
Applications Immunohistochemistry (Paraffin)
Classification Recombinant Monoclonal
Clone K40073_16B3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene ANKRD26P1
Gene Accession No. Q6NSI1
Gene Symbols ANKRD26P1
Host Species Mouse
Immunogen Recombinant human ANKRD26P1 (aa 171-300).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 124149
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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