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CD107a Rat anti-Mouse, FITC, Clone: 1D4B, BD
Rat Monoclonal Antibody
Brand: BD Biosciences 553793
This item is not returnable.
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Description
The 1D4B antibody recognizes CD107a (Lysosome-Associated Membrane Protein 1, LAMP-1), one of the two major glycoproteins in lysosome membranes which are useful markers to distinguish lysosomes from other organelles. Mouse CD107a consists of a 40kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. Several lines of evidence suggest that cell-surface mouse and human LAMP-1 glycoproteins, the expression of which may correlate with malignant transformation, participate in intercellular adhesion and adhesion to extracellular matrix.
Host Species: Rat
Clone: 1D4B
Isotype: IgG2a κ
Species Reactivity: Mouse
Immunogen: Plasma membrane fraction of mouse embryo NIH 3T3 cell line
Intracellular Staining
Specifications
| CD107a | |
| Monoclonal | |
| 0.5mg/mL | |
| LAMP-1; LGP-120; LGP-A; P2B | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| 1D4B | |
| FITC | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Plasma membrane fraction of mouse embryo NIH 3T3 cell line | |
| 0.5 mg | |
| Immunology | |
| Mouse | |
| IgG2a κ |
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