missing translation for 'onlineSavingsMsg'
Learn More
Learn More
CD16 Mouse anti-Human, Brilliant Violet 786, Clone: 3G8, BD
Mouse Monoclonal Antibody
224.70 € - 416.23 €
Specifications
| Antigen | CD16 |
|---|---|
| Clone | 3G8 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Conjugate | Brilliant Violet 786 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15892999
|
BD Biosciences
563689 |
25 Tests |
 225.00 € 224.70 € / Each Save 0.30 € 0.13% Off |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
|
15803009
|
BD Biosciences
563690 |
100 Tests |
435.00 € 416.23 € / Each Save 18.77 € 4% Off |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (Fc γRIII), a human NK cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes. The 3G8 antibody is reported (Vossebeld et al ., 1997) to increase intracellular calcium levels in human neutrophils by interacting with both Fc γRIIa and Fc γRIIIb molecules. This antibody has also been reported to induce homotypic neutrophil aggregation.
The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. This dye is a tandem fluorochrome of BD Horizon™ BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon™ BV786 can be excited by the violet laser and detected in a filter used to detect Cy7™-like dyes (eg, 780/60-nm filter).
Specifications
| CD16 | |
| Flow Cytometry | |
| Brilliant Violet 786 | |
| RUO | |
| Human polymorphonuclear leukocytes | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| 3G8 | |
| Monoclonal | |
| Mouse | |
| Baboon, Cynomolgus, Human, Rhesus Monkey | |
| IgG1 κ | |
| Affinity Purified | |
| FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3 |
For Research Use Only.
Spot an opportunity for improvement?Share a Content Correction
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title