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  6. EB1 Mouse, Unlabeled, Clone: 5, BD

EB1 Mouse, Unlabeled, Clone: 5, BD

Mouse Monoclonal Antibody

186.18 € - 476.00 €

Specifications

Antigen EB1
Clone 5
Concentration 250μg/mL
Applications Western Blot
Classification Monoclonal
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
15815509
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BD Biosciences
610534 		50 μg
ONLINE EXCLUSIVE PRICE
194.00 €
186.18 € / 1 set
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15825509
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BD Biosciences
610535 		150 μg
476.00 €
1 set
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Description

Description

Familial adenomatous polyposis is an autosomal inherited disease characterized by mutations in the APC (adenomatous polyposis coli) gene. Individuals with this disease are predisposed to colorectal polyps and cancer. It has been proposed that disruption of the APC gene plays a role in the disease. APC is a large coiled-coil protein that interacts, via its carboxy terminus, with catenins and with the protein, EB1. This 30kDa protein was discovered as a result of its strong binding to the C-terminal domain of APC. Like the APC-binding proteins β-Catenin and pp120Cas, EB1 may play an essential role in modulating APC activity and tumorigenesis.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Specifications

Specifications

EB1
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG1
Affinity Purified
5
Western Blot
Unconjugated
RUO
Chicken, Human, Mouse, Rat
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Store undiluted at -20°C.
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