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major histocompatibility complex, class II, DM alpha, Mouse, Polyclonal Antibody, Abnova™
Mouse polyclonal antibody raised against a full-length human HLA-DMA protein.
Brand: Abnova H00003108-B01.50uL
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Description
HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq
Sequence: MGHEQNQGAALLQMLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQQIGPKLDGKIPVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFRKPCSGDSpecifications
| major histocompatibility complex, class II, DM alpha | |
| Polyclonal | |
| Mouse polyclonal antibody raised against a full-length human HLA-DMA protein. | |
| HLA-DMA | |
| D6S222E/DMA/HLADM/RING6 | |
| Mouse | |
| 50 μL | |
| Membrane Receptors | |
| Primary | |
| Human | |
| Serum |
| Western Blot | |
| Unconjugated | |
| No additive | |
| NM_006120 | |
| HLA-DMA | |
| HLA-DMA (NP_006111, 1 a.a. ∼ 261 a.a) full-length human protein. | |
| RUO | |
| Yes | |
| 3108 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
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