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IL-12 (p40/p70) Mouse anti-Human, Biotin, Clone: C8.6, BD

Product Code. 15847828
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Product Code. 15847828 Supplier BD Biosciences Supplier No. 554660

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Description

Mouse Monoclonal Antibody

The C8.6 antibody reacts with human IL-12 p40 monomers, homodimers, and p70 heterodimers, but not p35 subunits. The immunogen used to generate the C8.6 hybridoma was the purified p40 subunit of human IL-12. The C8.6 antibody is a neutralizing antibody and has been reported to strongly inhibit three different biological activities of IL-12 (i.e., IFN-γ induction), mitogenic effects on PHA blasts, and enhancement of NK cell-mediated cytotoxicity. C8.6 has been shown to immunoprecipitate IL-23. This antibody is routinely tested by ELISA as a detection antibody. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: C8.6
Isotype: IgG1
Species Reactivity: Human
Immunogen: Purified p40 Subunit of Human IL-12

ELISA

TRUSTED_SUSTAINABILITY

Specifications

Antigen IL-12 (p40/p70)
Applications ELISA
Classification Monoclonal
Clone C8.6
Concentration 0.5mg/mL
Conjugate Biotin
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Purified p40 Subunit of Human IL-12
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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