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  6. Paxillin Mouse, Unlabeled, Clone: 165, BD

Paxillin Mouse, Unlabeled, Clone: 165, BD

Mouse Monoclonal Antibody

249.41 € - 323.14 €

Specifications

Antigen Paxillin
Clone 165
Concentration 250μg/mL
Applications Western Blot
Classification Monoclonal
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15815549
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BD Biosciences
610619 		50 μg
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BD Biosciences
610620 		150 μg
ONLINE EXCLUSIVE PRICE
336.00 €
323.14 € / 1 set
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Description

Description

Paxillin, a focal adhesion protein, is a substrate for several tyrosine kinases such as src, FAK, and p120BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. This is consisent with the possibility that paxillin is involved in the regulation of cell morphology. Additionally, because of its SH3 binding domain, paxillin associates tightly with FAK and Crk in an extracellular matrix-independent manner. Paxillin was initially detected in fibroblasts, and its phosphorylation may be important during neurite extension during differentiation.

This antibody is routinely tested by western blot analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Specifications

Specifications

Paxillin
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG1
Affinity Purified
165
Western Blot
Unconjugated
RUO
Canine, Chicken, Human, Mouse, Rat
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Store undiluted at -20°C.
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