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  6. RIP Mouse, Unlabeled, Clone: 38, BD

RIP Mouse, Unlabeled, Clone: 38, BD

Product Code. 15805479
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Quantity:
150 μg
50 μg
Unit Size:
1 set
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15805479 50 μg 1 set
15815479 150 μg 1 set
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Product Code. 15805479 Supplier BD Biosciences Supplier No. 610458

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Description

Mouse Monoclonal Antibody

Binding or cross linking of the Fas antigen (also known as APO-1 and CD95) is known to elicit apoptosis in susceptible cells. Fas is a member of a family of cell surface receptors which includes tumor necrosis factor receptors (TNF-R, and TNF-R2) and nerve growth factor receptors (NGF-R), CD40, OX40, CD30, CD27, and 4-1BB. Several members of this family have been shown to regulate or induce cell death (TNF-R1 and TNF-R2). A 74kDa member of this family protein named RIP (Receptor Interacting Protein) contains an N-terminal region with homology to protein kinases and a C-terminal region containing a cytoplasmic “death domain” present in both Fas and TNF-R1. Both Fas and RIP have been shown to require this death domain to induce apoptosis and overexpression of RIP has been shown to induce cell death in transfected cells.

Immunofluorescence, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen RIP
Applications Western Blot
Classification Monoclonal
Clone 38
Concentration 250μg/mL
Conjugate Unconjugated
Description Receptor Interacting Protein
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Canine, Chicken, Human, Mouse, Rat
Content And Storage Store undiluted at -20°C.
Isotype IgG2a
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For Research Use Only.

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