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Invitrogen™ APBA2 Monoclonal Antibody (1C12A4)
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Product Code. 16395054
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Quantity:
100 μL
Unit Size:
100µL
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16395054 100 μL 100µL
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Product Code. 16395054 Supplier Invitrogen™ Supplier No. MA531626

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Description

Mouse Monoclonal Antibody

MA5-31626 has been tested in indirect ELISA.

APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and is a neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimer's disease. It stabilizes APP and inhibits production of proteolytic APP fragments including the Abeta peptide that is deposited in the brains of Alzheimer's disease patients. APBA2 is believed to be involved in signal transduction processes and is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Recent reports suggest that it may also be a candidate gene for autism.
TRUSTED_SUSTAINABILITY

Specifications

Antigen APBA2
Applications ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 1C12A4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene APBA2
Gene Accession No. Q99767
Gene Alias Adapter protein X11beta; amyloid beta (A4) precursor protein-binding family A member 2 (X11-like); amyloid beta (A4) precursor protein-binding, family A, member 2; amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like); amyloid beta A4 precursor protein-binding family A member 2; amyloid beta precursor protein binding family A member 2; Amyloid-beta A4 precursor protein-binding family A member 2; Apba2; D15S1518E; HsT16821; LIN-10; MGC:14091; Mint 2; Mint2; mint-2; mXllL; Neuronal Munc18-1-interacting protein 2; neuron-specific X11L protein; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein; X11-BETA; X11L; X11-like; X11-like protein; XllL
Gene Symbols APBA2
Host Species Mouse
Immunogen Purified recombinant fragment of human APBA2 (AA: 15-158) expressed in E. coli.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 321
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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