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APTO-253, MedChemExpress

Product Code. p-200097025
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100 mg
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Product Code. 16497076

Brand: Medchem Express HY16291

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Description

MedChemExpress APTO-253 (LOR-253) is a small molecule that inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through induction of the Krüppel-like factor 4 (KLF4) tumor suppressor. APTO-253 has antiarthritic activity.

APTO-253 (LOR-253) is a small molecule that inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through induction of the Krüppel-like factor 4 (KLF4) tumor suppressor. APTO-253 has antiarthritic activity.

Specifications

Chemical Name or Material APTO-253
CAS 916151-99-0
Color Yellow
Purity Grade Notes Research
Molecular Formula C22H14FN5
Quantity 100 mg
Synonym LOR-253 LT-253
Solubility Information DMSO : 60 mg/mL (163.32 mM; Need ultrasonic)
SMILES CC(N1)=C(C(N2)=NC3=C2C4=CC=CN=C4C5=NC=CC=C53)C6=C1C=CC(F)=C6
Molecular Weight (g/mol) 367.38
Formula Weight 367.38
Percent Purity 98.15%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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