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Autophinib, MedChemExpress

Product Code. 16400037
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Product Code. 16400037

Brand: Medchem Express HY101920

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Description

MedChemExpress Autophinib is a potent, selective autophagy inhibitor with IC50s of 90 nM and 40 nM for starvation- and Rapamycin-induced autophagy, respectively. Autophinib is also an ATP competitive Vacuolar Protein Sorting 34 (VPS34) inhibitor with an IC50 of 19 nM. Autophinib inhibits autophagy induced by starvation or Rapamycin by targeting VPS34.

Autophinib is a potent, selective autophagy inhibitor with IC50s of 90 nM and 40 nM for starvation- and Rapamycin-induced autophagy, respectively. Autophinib is also an ATP competitive Vacuolar Protein Sorting 34 (VPS34) inhibitor with an IC50 of 19 nM. Autophinib inhibits autophagy induced by starvation or Rapamycin by targeting VPS34.

Specifications

Chemical Name or Material Autophinib
CAS 1644443-47-9
Color Yellow
Purity Grade Notes Research
Molecular Formula C14H11ClN6O3
Quantity 50 mg
Solubility Information DMSO : ≥ 30 mg/mL (86.52 mM)
SMILES CC1=CC(NC2=NC(OC3=CC=C([N+]([O-])=O)C=C3)=NC(Cl)=C2)=NN1
Molecular Weight (g/mol) 346.73
Formula Weight 346.73
Percent Purity 99.56%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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