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  8. AV-412 free base, MedChemExpress

AV-412 free base, MedChemExpress

Product Code. p-200097266
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Product Code. 16483848 Supplier Medchem Express Supplier No. HY10346A

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Description

MedChemExpress AV-412 free base (MP-412 free base) is an EGFR inhibitor with IC50s of 0.75, 0.5, 0.79, 2.3, 19 nM for EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M and ErbB2, respectively.

AV-412 free base (MP-412 free base) is an EGFR inhibitor with IC50s of 0.75, 0.5, 0.79, 2.3, 19 nM for EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M and ErbB2, respectively.

Specifications

Chemical Name or Material AV-412 free base
CAS 451492-95-8
Color Yellow
Purity Grade Notes Research
Molecular Formula C27H28ClFN6O
Quantity 10 mg
Synonym MP-412 free base
Solubility Information DMSO : 50 mg/mL (98.62 mM; Need ultrasonic)
SMILES O=C(C=C)NC1=CC2=C(NC3=CC=C(C(Cl)=C3)F)N=CN=C2C=C1C#CC(C)(C)N(CC4)CCN4C
Molecular Weight (g/mol) 507.0
Formula Weight 507.0
Percent Purity 98.33%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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