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Bcl-10 Antibody (BL10/411), Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-29422-20ug

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Product Code. 18453862

  • 260.00 € / 20µg

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Description

Description

Bcl-10 Monoclonal specifically detects Bcl-10 in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Bcl-10
Monoclonal
0.2 mg/ml
Western Blot 0.5-1 ug/mL, Flow Cytometry 0.5-1 ug/mL, ELISA 1-5 ug/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1-2 ug/mL, Immunoprecipitation 1-2 ug/500 ug protein lysate, Immunohistochemistry-Paraffin 0.5-1 ug/mL, Immunohistochemistry-Frozen 0.5-1 ug/mL
B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10, Bcl-10, CARD-containing apoptotic signaling protein, CARD-containing molecule enhancing NF-kappa-B, CARD-containing proapoptotic protein, CARD-like apoptotic protein, CARMEN, caspase-recruiting domain-containing protein, cCARMEN, c-E10bcl-10, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, cellular-E10, hCLAP, Mammalian CARD-containing adapter molecule E10, mE10CARD containing molecule enhancing NF-kB
Mouse
33 kDa
20 ug
Apoptosis, Cancer
8915
Human
Purified
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
BL10/411
Unconjugated
O95999
BCL10
Human Bcl-10 recombinant protein (epitope aa122-168) (Uniprot: O95999)
Protein A or G purified
RUO
Primary
BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFKB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
Store at 4C.
IgG1 κ
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