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Invitrogen™ BCL-XL Recombinant Rabbit Monoclonal Antibody (HL2038)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA556609
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Description
BCL-XL Recombinant Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)
BCL-XL is a part of the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BCL-XL is located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential and controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.
Specifications
| BCL-XL | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative | |
| P53563, Q07817, Q64373 | |
| BCL2L1 | |
| Recombinant fragment of human Bcl-XL. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat, Canine, Feline | |
| Antibody | |
| IgG |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| HL2038 | |
| Unconjugated | |
| BCL2L1 | |
| anti-apoptosis regulatory protein; apoptosis regulator Bcl-X; B cell lymphoma 2 like; B cell lymphoma like X; B-cell leukemia/lymphoma x; Bcl(X)L; BCL2 like 1; Bcl2l; BCL2L1; bcl2-L-1; BCL2-like 1; Bcl-2-like protein 1; BCLX; bcl-x; BCLXL; Bcl-XL; BCL-XL/S; BCLXS; bcl-xS; Blc2l; DKFZp781P2092; EGK_02534; OTTHUMP00000030550; OTTHUMP00000030552; OTTHUMP00000030555; OTTHUMP00000030556; OTTHUMP00000030557; PPP1R52; protein phosphatase 1, regulatory subunit 52; RP5-857M17.3 | |
| Rabbit | |
| Protein A | |
| RUO | |
| 12048, 24888, 403618, 493701, 598 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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