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Invitrogen™ BIKE Polyclonal Antibody
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Product Code. 17267673 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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17267673 100 μL 100µL
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Product Code. 17267673 Supplier Invitrogen™ Supplier No. PA5114911

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total BMP2K.

The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. BMP2K (BMP2 inducible kinase), also known as BIKE, is a 1,161 amino acid nuclear protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Thought to be involved in osteoblast differentiation, BMP2K catalyzes the ATP-dependent phosphorylation of bone morphogenic proteins (BMPs); proteins that are essential for proper cartilage and bone formation. Via its catalytic activity, BMP2K may play a role in signaling pathways that mediate bone growth and cellular differentiation. Three isoforms of BMP2K exist due to alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BIKE
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene BMP2K
Gene Accession No. Q91Z96, Q9NSY1
Gene Alias 4933417M22Rik; AA673486; AV128808; BIKE; Bike kinase; BMP2 inducible kinase; BMP-2 inducible kinase; BMP-2-inducible protein kinase; Bmp2k; HRIHFB2017
Gene Symbols BMP2K
Host Species Rabbit
Immunogen A synthesized peptide derived from human BMP2K(Accession Q9NSY1), corresponding to amino acid residues S599-R649.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140780, 498333, 55589
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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