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Invitrogen™ BMI-1 Monoclonal Antibody (A11-C11)

Mouse Monoclonal Antibody
Brand: Invitrogen™ MA534897
This item is not returnable.
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Description
Positive Control: Hela, NIH-3T3, SH-SY-5Y, human colon cancer tissue, mouse spleen tissue.
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Specifications
| BMI-1 | |
| Monoclonal | |
| 2 mg/mL | |
| PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4 | |
| P25916, P35226 | |
| BMI1 | |
| Recombinant protein within mouse Bmi1 aa 1-324. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG2a |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| A11-C11 | |
| Unconjugated | |
| BMI1 | |
| AW546694; B lymphoma Mo-MLV insertion region 1; B lymphoma Mo-MLV insertion region 1 homolog; Bmi1; Bmi-1; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; BMI1 proto-oncogene, polycomb ring finger; FLVI2/BMI1; flvi-2/bmi-1; murine leukemia viral (bmi-1) oncogene homolog; Pcgf4; Pcgf4 antibody; Polycomb complex protein BMI-1; polycomb group protein Bmi1; polycomb group ring finger 4; polycomb group RING finger protein 4; RING finger protein 51; RNF51; RP11-573G6.1 | |
| Mouse | |
| Affinity chromatography | |
| RUO | |
| 12151, 648 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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