missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ BMP-10 Monoclonal Antibody (654319)
Rat Monoclonal Antibody
Brand: Invitrogen™ MA561618
This item is not returnable.
View return policy
Description
Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. BMP-10 plays a crucial role in the development of the embryonic heart by acting to stimulate and maintain cardiomyocyte proliferation. It can signal through various receptor complexes usually containing BMPR-1A, BMPR-1B, ALK1, ALK3, or ALK6. The interaction of BMP-10 with its specific receptors can induce signaling initiated by the phosphorylation of SMAD transcription factors, including SMAD1, SMAD5, or SMAD8, but can also induce SMAD independent processes. BMP-10 is structurally related to BMP-9, and both can inhibit endothelial cell proliferation and migration.
Specifications
| BMP-10 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| Q9R229 | |
| BMP10 | |
| Chinese hamster ovary cell line CHO-derived recombinant human BMP-10, Asn314-Arg421. | |
| 100 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2a |
| Immunohistochemistry (Frozen) | |
| 654319 | |
| Unconjugated | |
| BMP10 | |
| BMP; BMP10; BMP-10; bmp10 {ECO:0000312; bmp10b; Bone morphogenetic protein; bone morphogenetic protein 10; EMBL:BAE16990.1, ECO:0000312; RGD:1562986}; si:dkey-13n15.5 | |
| Rat | |
| Protein A/G | |
| RUO | |
| 12154 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction