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Description
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase′s physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
Specifications
Specifications
| Antigen | BPNT1 |
| Applications | Immunofluorescence, Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.16 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | BPNT1 |
| Gene Accession No. | O95861, Q9Z0S1, Q9Z1N4 |
| Gene Alias | Bisphosphate 3 nucleotidase 1, BPNT1, PAP inositol 1,4 phosphatase, PIP |
| Gene Symbols | Bpnt1 |
| Show More |
Product Title
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