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C17orf37 Monoclonal Antibody (OTI1D7), TrueMAB™, OriGene

Product Code. 17541962
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100 μL
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17541962 100 μL 100µL
17561962 30 μL 30µL
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Product Code. 17541962 Supplier Origene Technologies Supplier No. TA504583

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Description

Mouse Monoclonal Antibody

During the past decade, the role of the ERBB2(neu/HER2) oncogene as an important predictor of patient outcome and response to various therapies in breast cancer has been clearly established. The C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer. Identification of shared tumor-specific targets is useful in developing broadly applicable therapies. The C35 gene is located on chromosome 17q12, 505nucleotides from the 3′ end of the ERBB2oncogene, the antigenic target for trastuzumab(Herceptin) therapy. The chromosomal arrangement of the genes encoding C35 andERBB2 is tail to tail. The ORF 37 open reading frame encodes a 12-kDa protein of unknown function.

Specifications

Antigen C17orf37
Applications Western Blot
Classification Monoclonal
Clone OTI1D7
Concentration 0.81 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene MIEN1
Gene Accession No. Q9BRT3
Gene Alias C17orf37, C35, ORB3, RDX12, XTP4
Gene Symbols MIEN1
Host Species Mouse
Immunogen Full length human recombit protein of human C17orf37 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84299
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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