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  6. Invitrogen™ Caspase 6 Recombinant Rabbit Monoclonal Antibody (K01_1K32)

Invitrogen™ Caspase 6 Recombinant Rabbit Monoclonal Antibody (K01_1K32)
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Product Code. p-200114055
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30824622 100 μL
30830458 50 μL
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Product Code. 30824622 Supplier Invitrogen™ Supplier No. MA563268

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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: AASVYTLPAG ADFLMCYSVA EGYYSHRETV NGSWYIQDLC EMLGKYGSSL EFTELLTLVN RKVSQRRVDF CKDPSAIGKK QVPCFASMLT KKLHFFPKSN Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 94%, Pig - 98%, Cynomolgus monkey - 100%.

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Caspase 6
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_1K32
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 40% glycerol, 0.05% BSA, 150mM NaCl and 0.01% sodium azide; pH 7.4
Gene Casp6
Gene Accession No. O35397, P55212
Gene Alias apoptotic protease MCH-2; CASP6; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; caspase-6; Caspase-6 subunit p11; Caspase-6 subunit p18; mCASP-6; MCH2
Gene Symbols Casp6
Host Species Rabbit
Immunogen Recombinant protein of human Caspase-6 (aa 194-293).
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 83584, 839
Target Species Human, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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