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CD106 (VCAM-1) Monoclonal Antibody (STA), eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-1069-95

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Product Code. 17190542

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Description

Description

Description: The STA monoclonal antibody reacts with human CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to Integrin alpha4beta1 (VLA-4, CD49d/CD29) and Integrin alpha4beta7 (LPAM-1). Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response. Applications Reported: STA has been reported for use in flow cytometric analysis, and immunohistochemical staining of frozen tissue sections. Applications Tested: The STA antibody has been tested by flow cytometric analysis of TNF alpha-activated HUVEC cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.

CD106 (VCAM-1) Monoclonal antibody specifically detects CD106 (VCAM-1) in Human samples. It is validated for Flow Cytometry, Immunohistochemistry (Frozen)
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD106 (VCAM-1)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P19320
Mouse
10 mg
Primary
Human
Antibody
IgG1 κ
Flow Cytometry, Immunohistochemistry (Frozen)
STA
Unconjugated
VCAM1
adhesion molecule VCAM-1; CD106; CD106 antigen; DKFZp779G2333; INCAM100; INCAM-100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; vascular cell adhesion molecule; vascular cell adhesion molecule 1; vascular cell adhesion molecule-1; vascular cell adhesion protein 1; V-CAM 1; VCAM1; Vcam-1; VCAM1B
Affinity chromatography
RUO
7412
4° C
Liquid
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